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Alzheimer's Disease Neuroimaging Initiative

Letter of Welcome from the ADNI Principal Investigator

Welcome to the Home Page of the Alzheimer's Disease Neuroimaging Initiative.

The overall goal of this huge project is to define the rate of progress of mild cognitive impairment and Alzheimer's disease, to develop improved methods for clinical trials in this area, and to provide a large database which will improve design of treatment trials. We expect that this project will provide information and methods which will help lead to effective treatments for Alzheimer’s disease, leading to effective prevention.

This study is a large five year (we began on Oct 1 2004) research project to study the rate of change of cognition, function, brain structure and function, and biomarkers in 200 elderly controls, 400 subjects with mild cognitive impairment, and 200 with Alzheimer’s disease. There will be public access of the clinical and imaging data through this website and a parallel website at the Laboratory of Neuroimaging. Our project is funded for $60 million, with $40 million from the National Institute of Aging and National Institute of Bioimaging and Bioengineering, and $20 million from the Pharmaceutical Industry and several foundations, donated to the Foundation for NIH. The funds are awarded to the Northern California Institute for Research and Education, which is located at the Veterans Administration Medical Center, San Francisco, affiliated with the University of California San Francisco.

Our website has two sections:
First, information for the general public interested in learning more about this project, and who may want to participate as volunteers.  The second section contains information for scientists who want more technical information, or who wish to access our data bases. Scientists should go to the "Scientist page”.

For those who have questions about this project, I strongly encourage you to read the various components of this website.
Individuals who wish to volunteer as participants can find appropriate contact information by clicking here.

For scientists who want more information, they should read the grant application (which is within the Scientist Section), and also read the complete protocol  and the procedures manuals for the Clinical, MRI, and PET cores.

For individuals who have additional questions about recruitment, contact Ann Wehling This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

For investigators who have additional questions about the ADNI, they should contact myself or the relevant Core Leader.  Contact information is provided within the Scientist Section.

For questions about this site please email This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Please let us know your suggestions for how we can increase the impact and success of ADNI.

Michael W. Weiner MD
Principal Investigator, Alzheimer's Disease Neuroimaging Initiative
Director, Center for Imaging of Neurodegenerative Disease
VA Medical Center (114M)
4150 Clement St., San Francisco Ca. 94121 USA
Professor of Medicine, Radiology, Psychiatry, and Neurology
University of California, San Francisco, U.S.A.
Web site for Dr Weiner's Laboratory
 
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