ADNI and UDS
ADNI Measures and the Uniform Data Set (UDS)
Logical Memory: Immediate and Delayed Recall
ADAS-Cog (Part 1)
ADAS-Cog (Part 2)
Clock Drawing and Clock Copying
Rey's Auditory Verbal Learning Test
Digits Forward and Digits Backward
Verbal Fluency (Animals and Vegetables)
Trail Making (Parts A and B)
Digit Symbol Substitution
Boston Naming Test
American National Adult Reading Test (ANART)
The tests and scales were chosen for use in this protocol because:
- They represent the domains of interest in this patient population
- They adequately sample cognitive domains of interest in subjects who are normal, or have MCI or AD
- Are able to measure change over two to three years in these patient populations
- Subjects enrolled will not demonstrate floor or ceiling effects
- Are reasonably efficient and can meet the practical demands of the proposed study
- Were utilized previously in the ADCS MCI trial and worked well.
All of these instruments are widely used in multi-center trials studying normals, MCI, and early AD subjects. Additionally, they are being used by Alzheimer Disease Centers as part of their collection of a Uniform Data Set (UDS) thereby reducing the amount of testing that subjects will need to undergo who are enrolled in both ADC’s and ADNI.
The Uniform Data Set is part of the collaborative research facilitated by the National Alzheimer's Coordinating Center (NACC) among approximately 30 Alzheimer's Disease Centers funded by the National Institute on Aging.
Email for help with Uniform Data Set (UDS):
Questions about the Uniform Data Set?
Researchers affiliated with ADCs may access the UDS neuropsychology forms and Coding Guidebook at https://www.alz.washington.edu/MEMBER/uds.html. Access to these documents is password-restricted to NACC members only (to obtain membership, contact NACC at 206-543-8637 or